Scientific articles

Modern approaches to the diagnosis and treatment of diarrheal diseases

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Author: Golubovska O. A., Head of the Department of Infectious Diseases at Bogomolets National Medical University, Doctor of Medical Sciences, Professor, Honored Doctor of Ukraine


According to WHO data, there are approximately 2 billion cases of diarrhea worldwide each year. Up to 30% of the population of industrialized countries suffers from foodborne diseases, 80–85% of which are caused by infectious agents. Currently, the most “deadly” pathogens of intestinal infections in the world are S. typhi, enteropathogenic E. coli, and noroviruses (52,000, 37,000, and 35,000 deaths per year, respectively).

Any diarrhea is the result of the predominance of water and electrolyte secretion over absorption in the intestine. Four main mechanisms are involved in the pathogenesis of diarrhea: intestinal secretion, increased osmotic pressure in the intestinal cavity, impaired transit of intestinal contents, and intestinal exudation.

The unique combination of probiotics in Opfer has a synergistic effect. The waste products of Streptococcus thermophilus support the growth and reproduction of lactobacilli. In turn, the acidic environment created by lactobacilli is optimal for bifidobacteria, the main component of normal intestinal microflora.

Published in the journal «District Doctor» ‘2017